Divergent Roles of CYP26B1 and Endogenous Retinoic Acid in Mouse Fetal Gonads

In female mammals, germ cells enter meiosis in the fetal ovaries, while in males, meiosis is prevented until postnatal development. Retinoic acid (RA) is considered the main inducer of meiotic entry, as it stimulates Stra8 which is required for the mitotic/meiotic switch. In fetal testes, the RA-deg...

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Veröffentlicht in:Biomolecules
Hauptverfasser: Bellutti, Laura, Abby, Emilie, Tourpin, Sophie, Messiaen, Sébastien, Moison, Delphine, Trautmann, Emilie, Guerquin, Marie-Justine, Rouiller-Fabre, Virginie, Habert, René, Livera, Gabriel
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6843241/
https://ncbi.nlm.nih.gov/pubmed/31561560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9100536
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