Divergent Roles of CYP26B1 and Endogenous Retinoic Acid in Mouse Fetal Gonads

In female mammals, germ cells enter meiosis in the fetal ovaries, while in males, meiosis is prevented until postnatal development. Retinoic acid (RA) is considered the main inducer of meiotic entry, as it stimulates Stra8 which is required for the mitotic/meiotic switch. In fetal testes, the RA-deg...

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Publicat a:Biomolecules
Autors principals: Bellutti, Laura, Abby, Emilie, Tourpin, Sophie, Messiaen, Sébastien, Moison, Delphine, Trautmann, Emilie, Guerquin, Marie-Justine, Rouiller-Fabre, Virginie, Habert, René, Livera, Gabriel
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6843241/
https://ncbi.nlm.nih.gov/pubmed/31561560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9100536
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