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Renoprotective impact of estrogen receptor-α and its splice variants in female mice with type 1 diabetes

Estrogen has been implicated in the regulation of growth and immune function in the kidney, which expresses the full-length estrogen receptor-α (ERα66), its ERα splice variants, and estrogen receptor-β (ERβ). Thus, we hypothesized that these splice variants may inhibit the glomerular enlargement tha...

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Détails bibliographiques
Publié dans:Am J Physiol Renal Physiol
Auteurs principaux: Irsik, Debra L., Romero-Aleshire, Melissa J., Chavez, Erin M., Fallet, Rachel W., Brooks, Heddwen L., Carmines, Pamela K., Lane, Pascale H.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842867/
https://ncbi.nlm.nih.gov/pubmed/29667912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00231.2017
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