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A novel missense in GLI3 possibly affecting one of the zinc finger domains may lead to postaxial synpolydactyly: case report

BACKGROUND: Polydactyly is one of the most common congenital hand/foot malformations in humans. Mutations in GLI3 have been reported to cause syndromic and non-syndromic forms of preaxial and postaxial polydactylies. CASE PRESENTATION: The patient was a 2-year-old boy who underwent surgery in our ho...

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Detalhes bibliográficos
Publicado no:BMC Med Genet
Main Authors: Zou, Qianqian, Tian, Zhigang, Zheng, Jie, Zhi, Xiufang, Du, Xiaojie, Shu, Jianbo, Cai, Chunquan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842497/
https://ncbi.nlm.nih.gov/pubmed/31706290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-019-0889-5
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