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Asymmetric centromeres differentially coordinate with mitotic machinery to ensure biased sister chromatid segregation in germline stem cells

Many stem cells utilize asymmetric cell division (ACD) to produce a self-renewed stem cell and a differentiating daughter cell. How non-genic information could be inherited differentially to establish distinct cell fates is not well understood. Here, we report a series of spatiotemporally regulated...

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Veröffentlicht in:Cell Stem Cell
Hauptverfasser: Ranjan, Rajesh, Snedeker, Jonathan, Chen, Xin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842444/
https://ncbi.nlm.nih.gov/pubmed/31564548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2019.08.014
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