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Randomized Comparison Study of Novel Recombinant Human Antithrombin Gamma and Plasma-Derived Antithrombin in Healthy Volunteers

BACKGROUND AND OBJECTIVE: This paper describes two studies, which aimed to compare the safety and plasma antithrombin activity of recombinant human antithrombin gamma (rhAT-gamma) with plasma-derived antithrombin (pAT) 60 IU/kg, and to establish bioequivalence by adjusting the rhAT-gamma dose to tha...

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Publicat a:Clin Drug Investig
Autors principals: Furuie, Hidetoshi, Kanda, Hironori
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842348/
https://ncbi.nlm.nih.gov/pubmed/31493216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40261-019-00847-9
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