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PSMD1 and PSMD2 regulate HepG2 cell proliferation and apoptosis via modulating cellular lipid droplet metabolism

BACKGROUND: Obesity and nonalcoholic steatohepatitis (NASH) are well-known risk factors of hepatocellular carcinoma (HCC). The lipid-rich environment enhances the proliferation and metastasis abilities of tumor cells. Previous studies showed the effect of the ubiquitin–proteasome system (UPS) on tum...

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Detalhes bibliográficos
Publicado no:BMC Mol Biol
Main Authors: Tan, Yanjie, Jin, Yi, Wu, Xiang, Ren, Zhuqing
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842266/
https://ncbi.nlm.nih.gov/pubmed/31703613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12867-019-0141-z
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