Total saponins of Bolbostemma paniculatum (maxim.) Franquet exert antitumor activity against MDA-MB-231 human breast cancer cells via inhibiting PI3K/Akt/mTOR pathway

BACKGROUND: The aim of the present study was to examine the effects of the Bolbostemma paniculatum (Maxim.) Franquet (BP) active compound, BP total saponins (BPTS), on MDA-MB-231 cells, and investigate the underlying mechanism regarding BPTS-mediated attenuation of the PI3K/Akt/mTOR pathway. METHODS...

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Detalhes bibliográficos
Publicado no:BMC Complement Altern Med
Main Authors: Dou, Jian-Wei, Shang, Rong-Guo, Lei, Xiao-Qin, Li, Kang-Le, Guo, Zhan-Zi, Ye, Kai, Yang, Xiao-Juan, Li, Yu-Wei, Zhou, Yun-Yun, Yao, Jia, Huang, Qian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842232/
https://ncbi.nlm.nih.gov/pubmed/31703679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12906-019-2708-0
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