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A comparative analysis of RNA sequencing methods with ribosome RNA depletion for degraded and low-input total RNA from formalin-fixed and paraffin-embedded samples

BACKGROUND: Formalin-fixed and paraffin-embedded (FFPE) blocks held in clinical laboratories are an invaluable resource for clinical research, especially in the era of personalized medicine. It is important to accurately quantitate gene expression with degraded and small amounts of total RNA from FF...

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Bibliographic Details
Published in:BMC Genomics
Main Authors: Lin, Xiaojing, Qiu, Lihong, Song, Xue, Hou, Junyan, Chen, Weizhi, Zhao, Jun
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842158/
https://ncbi.nlm.nih.gov/pubmed/31703614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-019-6166-3
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