Phase Separation-mediated TARP/MAGUK Complex Condensation and AMPA Receptor Synaptic Transmission

Transmembrane AMPAR regulatory proteins (TARPs) modulate AMPAR synaptic trafficking and transmission via disc-large (DLG) subfamily of membrane-associated guanylate kinases (MAGUKs). Despite extensive studies, the molecular mechanism governing specific TARP/MAGUK interaction remains elusive. Using S...

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Publicat a:Neuron
Autors principals: Zeng, Menglong, Díaz-Alonso, Javier, Ye, Fei, Chen, Xudong, Xu, Jia, Ji, Zeyang, Nicoll, Roger A., Zhang, Mingjie
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842113/
https://ncbi.nlm.nih.gov/pubmed/31492534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2019.08.001
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