Glial cell line-derived neurotrophic factor (GDNF) mediates hepatic stellate cell activation via ALK5/Smad signalling

OBJECTIVE: Although glial cell line-derived neurotrophic factor (GDNF) is a member of the transforming growth factor-β superfamily, its function in liver fibrosis has rarely been studied. Here, we investigated the role of GDNF in hepatic stellate cell (HSC) activation and liver fibrosis in humans an...

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Detalhes bibliográficos
Publicado no:Gut
Main Authors: Tao, Le, Ma, Wenting, Wu, Liu, Xu, Mingyi, Yang, Yanqin, Zhang, Wei, Sha, Wenjun, Li, Hongshan, Xu, Jianrong, Feng, Rilu, Xue, Dongying, Zhang, Jie, Dooley, Steven, Seki, Ekihiro, Liu, Ping, Liu, Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2019
Assuntos:
Hepatology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842044/
https://ncbi.nlm.nih.gov/pubmed/31171625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2018-317872
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