Early life stress alters transcriptomic patterning across reward circuitry in male and female mice

Abuse, neglect, and other forms of early life stress (ELS) significantly increase risk for psychiatric disorders including depression. In this study, we show that ELS in a postnatal sensitive period increases sensitivity to adult stress in female mice, consistent with our earlier findings in male mi...

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Udgivet i:Nat Commun
Main Authors: Peña, Catherine Jensen, Smith, Milo, Ramakrishnan, Aarthi, Cates, Hannah M., Bagot, Rosemary C., Kronman, Hope G., Patel, Bhakti, Chang, Austin B., Purushothaman, Immanuel, Dudley, Joel, Morishita, Hirofumi, Shen, Li, Nestler, Eric J.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6841985/
https://ncbi.nlm.nih.gov/pubmed/31704941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13085-6
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