PathTracer: High-sensitivity detection of differential pathway activity in tumours

Gene expression profiling of tumours is an important source of information for cancer patient stratification. Detecting subtle alterations of gene expression remains a challenge, however. Here, we propose a novel tool for high-sensitivity detection of differential pathway activity in tumours. For a...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Nygård, Ståle, Lingjærde, Ole Christian, Caldas, Carlos, Hovig, Eivind, Børresen-Dale, Anne-Lise, Helland, Åslaug, Haakensen, Vilde D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6841931/
https://ncbi.nlm.nih.gov/pubmed/31704995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52529-3
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