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Aberrant DNA methylation of miRNAs in Fuchs endothelial corneal dystrophy

Homeostatic maintenance of corneal endothelial cells is essential for maintenance of corneal deturgescence and transparency. In Fuchs endothelial corneal dystrophy (FECD), an accelerated loss and dysfunction of endothelial cells leads to progressively severe visual impairment. An abnormal accumulati...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Pan, Peipei, Weisenberger, Daniel J., Zheng, Siyu, Wolf, Marie, Hwang, David G., Rose-Nussbaumer, Jennifer R., Jurkunas, Ula V., Chan, Matilda F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6841734/
https://ncbi.nlm.nih.gov/pubmed/31705138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52727-z
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