Aberrant DNA methylation of miRNAs in Fuchs endothelial corneal dystrophy

Homeostatic maintenance of corneal endothelial cells is essential for maintenance of corneal deturgescence and transparency. In Fuchs endothelial corneal dystrophy (FECD), an accelerated loss and dysfunction of endothelial cells leads to progressively severe visual impairment. An abnormal accumulati...

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Publicat a:Sci Rep
Autors principals: Pan, Peipei, Weisenberger, Daniel J., Zheng, Siyu, Wolf, Marie, Hwang, David G., Rose-Nussbaumer, Jennifer R., Jurkunas, Ula V., Chan, Matilda F.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6841734/
https://ncbi.nlm.nih.gov/pubmed/31705138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52727-z
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