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Functionalized azetidines via visible light-enabled aza Paternò-Büchi reactions

Azetidines are four-membered nitrogen-containing heterocycles that hold great promise in current medicinal chemistry due to their desirable pharmacokinetic effects. However, a lack of efficient synthetic methods to access functionalized azetidines has hampered their incorporation into pharmaceutical...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Becker, Marc R., Richardson, Alistair D., Schindler, Corinna S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6841681/
https://ncbi.nlm.nih.gov/pubmed/31704919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13072-x
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