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Regulation of CHD2 expression by the Chaserr long noncoding RNA gene is essential for viability

Chromodomain helicase DNA binding protein 2 (Chd2) is a chromatin remodeller implicated in neurological disease. Here we show that Chaserr, a highly conserved long noncoding RNA transcribed from a region near the transcription start site of Chd2 and on the same strand, acts in concert with the CHD2...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Rom, Aviv, Melamed, Liliya, Gil, Noa, Goldrich, Micah Jonathan, Kadir, Rotem, Golan, Matan, Biton, Inbal, Perry, Rotem Ben-Tov, Ulitsky, Igor
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6841665/
https://ncbi.nlm.nih.gov/pubmed/31704914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13075-8
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