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GENOMIC ANALYSIS OF HUMAN ISOGENIC APOE IPSC-DERIVED INHIBITORY GABAERGIC NEURONS
Isoforms of ApoE modify the risk for Alzheimer’s disease (AD), cardiovascular disease and are also associated with exceptional longevity. Specifically, the ApoE E2 allele is associated with lower risk of AD-related neurodegeneration and with exceptional longevity, while the E4 allele is a major risk...
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| Publicado no: | Innov Aging |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6841494/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igz038.2315 |
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