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JUMP AROUND, JUMP AROUND: TRANSPOSABLE ELEMENT ACTIVATION IN NEURODEGENERATIVE TAUOPATHY

Transposable elements, or “jumping genes,” constitute ~45% of the human genome. We have identified transposable element activation as a key mediator of neurodegeneration in tauopathies, a group of disorders that are pathologically defined by deposits of tau protein in the brain. Cellular defenses th...

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Detalhes bibliográficos
Publicado no:Innov Aging
Main Authors: Frost, Bess E, Sun, Wenyan, Samimi, Hanie, Zare, Habil
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6841180/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igz038.2178
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