DNA methylation defines regional identity of human intestinal epithelial organoids and undergoes dynamic changes during development

OBJECTIVE: Human intestinal epithelial organoids (IEOs) are increasingly being recognised as a highly promising translational research tool. However, our understanding of their epigenetic molecular characteristics and behaviour in culture remains limited. DESIGN: We performed genome-wide DNA methyla...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Gut
Main Authors: Kraiczy, Judith, Nayak, Komal M, Howell, Kate J, Ross, Alexander, Forbester, Jessica, Salvestrini, Camilla, Mustata, Roxana, Perkins, Sally, Andersson-Rolf, Amanda, Leenen, Esther, Liebert, Anke, Vallier, Ludovic, Rosenstiel, Philip C, Stegle, Oliver, Dougan, Gordon, Heuschkel, Robert, Koo, Bon-Kyoung, Zilbauer, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2019
Assuntos:
Intestinal Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6839835/
https://ncbi.nlm.nih.gov/pubmed/29141958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2017-314817
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados