Distinct serum biosignatures are associated with different tuberculosis treatment outcomes

Biomarkers for TB treatment response and outcome are needed. This study characterize changes in immune profiles during TB treatment, define biosignatures associated with treatment outcomes, and explore the feasibility of predictive models for relapse. Seventy-two markers were measured by multiplex c...

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Pubblicato in:Tuberculosis (Edinb)
Autori principali: Ronacher, Katharina, Chegou, Novel N., Kleynhans, Léanie, Djoba Siawaya, Joel F., du Plessis, Nelita, Loxton, André G., Maasdorp, Elizna, Tromp, Gerard, Kidd, Martin, Stanley, Kim, Kriel, Magdalena, Menezes, Angela, Gutschmidt, Andrea, van der Spuy, Gian D., Warren, Robin M., Dietze, Reynaldo, Okwera, Alphonse, Thiel, Bonnie, Belisle, John T., Cliff, Jacqueline M., Boom, W. Henry, Johnson, John L., van Helden, Paul D., Dockrell, Hazel M., Walzl, Gerhard
Natura: Artigo
Lingua:Inglês
Pubblicazione: Churchill Livingstone 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6839616/
https://ncbi.nlm.nih.gov/pubmed/31434026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tube.2019.101859
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