24S-Hydroxycholesterol Is Associated with Agitation Severity in Patients with Moderate-to-Severe Alzheimer’s Disease: Analyses from a Clinical Trial with Nabilone

BACKGROUND: Agitation is a prevalent and difficult-to-treat symptom of Alzheimer’s disease (AD). The endocannabinoid system (ECS) has been a target of interest for the treatment of agitation. However, ECS signaling may interact with AD-related changes in brain cholesterol metabolism. Elevated brain...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Ruthirakuhan, Myuri, Herrmann, Nathan, Andreazza, Ana C., Verhoeff, Nicolaas Paul L.G., Gallagher, Damien, Black, Sandra E., Kiss, Alex, Lanctôt, Krista L.
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6839471/
https://ncbi.nlm.nih.gov/pubmed/31322567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-190202
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