Quantitative Spatial Analysis of Metabolic Heterogeneity Across in vivo and in vitro Tumor Models

Metabolic preferences of tumor cells vary within a single tumor, contributing to tumor heterogeneity, drug resistance, and patient relapse. However, the relationship between tumor treatment response and metabolically distinct tumor cell populations is not well-understood. Here, a quantitative approa...

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Bibliographic Details
Published in:Front Oncol
Main Authors: Heaster, Tiffany M., Landman, Bennett A., Skala, Melissa C.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Oncology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6839277/
https://ncbi.nlm.nih.gov/pubmed/31737571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01144
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