Quercetin prevents necroptosis of oligodendrocytes by inhibiting macrophages/microglia polarization to M1 phenotype after spinal cord injury in rats

BACKGROUND: Oligodendrocytes (OLs) death after spinal cord injury (SCI) contributes to demyelination, even leading to a permanent neurological deficit. Besides apoptosis, our previous study demonstrated that OLs underwent receptor-interacting serine-threonine kinase 3(RIP3)/mixed lineage kinase doma...

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Detalles Bibliográficos
Publicado en:J Neuroinflammation
Main Authors: Fan, Hong, Tang, Hai-Bin, Shan, Le-Qun, Liu, Shi-Chang, Huang, Da-Geng, Chen, Xun, Chen, Zhe, Yang, Ming, Yin, Xin-Hua, Yang, Hao, Hao, Ding-Jun
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6839267/
https://ncbi.nlm.nih.gov/pubmed/31699098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1613-2
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