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Targeting of CXCR3 improves anti-myeloma efficacy of adoptively transferred activated natural killer cells

BACKGROUND: The peculiar multiple myeloma microenvironment, characterized by up-regulated levels of several inflammatory chemokines, including the CXCR3 receptor ligands CXCL9 and CXCL10, limits NK cell positioning into the bone marrow by interfering with CXCR4 function. It is still unclear if the c...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Bonanni, Valentina, Antonangeli, Fabrizio, Santoni, Angela, Bernardini, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6839099/
https://ncbi.nlm.nih.gov/pubmed/31699153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-019-0751-5
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