β-Cyclodextrin complex improves the bioavailability and antitumor potential of cirsiliol, a flavone isolated from Leonotis nepetifolia (Lamiaceae)

Cirsiliol is a flavone found in many Lamiaceae species with high cytotoxic activity against tumor cell lines. Although cirsiliol is being used in cancer therapy, its pharmacological potential is limited by its low solubility and bioavailability. In this paper, a cirsiliol-β-cyclodextrin inclusion co...

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Detaylı Bibliyografya
Yayımlandı:Heliyon
Asıl Yazarlar: Oliveira, Ana P., Silva, Andressa L.N., Viana, Lucas G.F.C., Silva, Mariana G., Lavor, Érica M., Oliveira-Júnior, Raimundo G., Alencar-Filho, Edilson B., Lima, Ricardo S., Mendes, Rosemairy L., Rolim, Larissa A., Anjos, Débora S.C., Ferraz, Leslie R.M., Rolim-Neto, Pedro J., Silva, Maria F.S., Pessoa, Claudia do Ó., Almeida, Jackson R.G.S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6838880/
https://ncbi.nlm.nih.gov/pubmed/31720439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2019.e01692
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