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Chondral Differentiation of Induced Pluripotent Stem Cells Without Progression Into the Endochondral Pathway

A major problem with chondrocytes derived in vitro from stem cells is undesired hypertrophic degeneration, to which articular chondrocytes (ACs) are resistant. As progenitors of all adult tissues, induced pluripotent stem cells (iPSCs) are in theory able to form stable articular cartilage. In vitro...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Diederichs, Solvig, Klampfleuthner, Felicia A. M., Moradi, Babak, Richter, Wiltrud
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6838640/
https://ncbi.nlm.nih.gov/pubmed/31737632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2019.00270
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