Reductions in COQ2 Expression Relate to Reduced ATP Levels in Multiple System Atrophy Brain

Multiple system atrophy (MSA) is a progressive neurodegenerative disease clinically characterized by parkinsonism and cerebellar ataxia, and pathologically by oligodendrocyte α-synuclein inclusions. Genetic variants of COQ2 are associated with an increased risk for MSA in certain populations. Also,...

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Gepubliceerd in:Front Neurosci
Hoofdauteurs: Hsiao, Jen-Hsiang T., Purushothuman, Sivaraman, Jensen, Poul H., Halliday, Glenda M., Kim, Woojin Scott
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2019
Onderwerpen:
Neuroscience
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6838639/
https://ncbi.nlm.nih.gov/pubmed/31736705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.01187
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