Characterization of plasma-derived protoporphyrin-IX-positive extracellular vesicles following 5-ALA use in patients with malignant glioma

BACKGROUND: Malignant gliomas are rapidly progressive brain tumors with high mortality. Fluorescence guided surgery (FGS) with 5-aminolevulinic acid (5-ALA) provides fluorescent delineation of malignant tissue, which helps achieve maximum safe resection. 5-ALA-based fluorescence is due to preferenti...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Jones, Pamela S., Yekula, Anudeep, Lansbury, Elizabeth, Small, Julia L., Ayinon, Caroline, Mordecai, Scott, Hochberg, Fred H., Tigges, John, Delcuze, Bethany, Charest, Alain, Ghiran, Ionita, Balaj, Leonora, Carter, Bob S.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6838454/
https://ncbi.nlm.nih.gov/pubmed/31628025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.09.025
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