Hepatic encephalopathy is linked to alterations of autophagic flux in astrocytes

BACKGROUND: Hepatic encephalopathy (HE) is a severe neuropsychiatric syndrome caused by various types of liver failure resulting in hyperammonemia-induced dysfunction of astrocytes. It is unclear whether autophagy, an important pro-survival pathway, is altered in the brains of ammonia-intoxicated an...

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Bibliografische gegevens
Gepubliceerd in:EBioMedicine
Hoofdauteurs: Lu, Kaihui, Zimmermann, Marcel, Görg, Boris, Bidmon, Hans-Jürgen, Biermann, Barbara, Klöcker, Nikolaj, Häussinger, Dieter, Reichert, Andreas S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2019
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Research paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6838440/
https://ncbi.nlm.nih.gov/pubmed/31648987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.09.058
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