High levels of serum hyaluronan is an early predictor of dengue warning signs and perturbs vascular integrity

BACKGROUND: A main pathological feature of severe dengue virus infection is endothelial hyper-permeability. The dengue virus nonstructural protein 1 (NS1) has been implicated in the vascular leakage that characterizes severe dengue virus infection, however, the molecular mechanisms involved are not...

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Bibliographic Details
Published in:EBioMedicine
Main Authors: Lin, Chun-Yu, Kolliopoulos, Constantinos, Huang, Chung-Hao, Tenhunen, Jyrki, Heldin, Carl-Henrik, Chen, Yen-Hsu, Heldin, Paraskevi
Format: Artigo
Language:Inglês
Published: Elsevier 2019
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Research paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6838418/
https://ncbi.nlm.nih.gov/pubmed/31526718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.09.014
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