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Discovery of Novel Multi-target Inhibitor of angiotensin type 1 receptor and neprilysin inhibitors from Traditional Chinese Medicine

Angiotensin II type-1 receptor–neprilysin inhibitor (ARNi) is consisted of Angiotensin II type-1 receptor (AT1) antagonist and neprilysin (NEP) inhibitor, which could simultaneously increase the vasodilators of the natriuretic peptides and antagonize vasoconstrictors of Ang II. ARNi has been proved...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Huo, Xiaoqian, Qiao, Liansheng, Chen, Yankun, Chen, Xi, He, Yusu, Zhang, Yanling
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6838339/
https://ncbi.nlm.nih.gov/pubmed/31700033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52309-z
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