Foxp1 controls brown/beige adipocyte differentiation and thermogenesis through regulating β3-AR desensitization

β-Adrenergic receptor (β-AR) signaling is a pathway controlling adaptive thermogenesis in brown or beige adipocytes. Here we investigate the biological roles of the transcription factor Foxp1 in brown/beige adipocyte differentiation and thermogenesis. Adipose-specific deletion of Foxp1 leads to an i...

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Publicado no:Nat Commun
Main Authors: Liu, Pei, Huang, Sixia, Ling, Shifeng, Xu, Shuqin, Wang, Fuhua, Zhang, Wei, Zhou, Rujiang, He, Lin, Xia, Xuechun, Yao, Zhengju, Fan, Ying, Wang, Niansong, Hu, Congxia, Zhao, Xiaodong, Tucker, Haley O., Wang, Jiqiu, Guo, Xizhi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6838312/
https://ncbi.nlm.nih.gov/pubmed/31699980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12988-8
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