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What Is Karyotype Coding and Why Is Genomic Topology Important for Cancer and Evolution?

While the importance of chromosomal/nuclear variations vs. gene mutations in diseases is becoming more appreciated, less is known about its genomic basis. Traditionally, chromosomes are considered the carriers of genes, and genes define bio-inheritance. In recent years, the gene-centric concept has...

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Библиографические подробности
Опубликовано в: :Front Genet
Главные авторы: Ye, Christine J., Stilgenbauer, Lukas, Moy, Amanda, Liu, Guo, Heng, Henry H.
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6838208/
https://ncbi.nlm.nih.gov/pubmed/31737054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.01082
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