Defining the Celiac Disease Transcriptome using Clinical Pathology Specimens Reveals Biologic Pathways and Supports Diagnosis

Celiac disease is provoked by gluten exposure, but the complete pathogenic process in the duodenum and the loss of tolerance to gluten is not well understood. We aimed to define the core celiac transcriptomic signature and pathologic pathways in pre-treatment formalin-fixed paraffin-embedded (FFPE)...

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Vydáno v:Sci Rep
Hlavní autoři: Loberman-Nachum, Nurit, Sosnovski, Katya, Di Segni, Ayelet, Efroni, Gilat, Braun, Tzipi, BenShoshan, Marina, Anafi, Lait, Avivi, Camila, Barshack, Iris, Shouval, Dror S., Denson, Lee A., Amir, Amnon, Unger, Ron, Weiss, Batia, Haberman, Yael
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6838157/
https://ncbi.nlm.nih.gov/pubmed/31700112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52733-1
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