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Double deficiency of toll-like receptors 2 and 4 alters long-term neurological sequelae in mice cured of pneumococcal meningitis

Toll-like receptor (TLR) 2 and 4 signalling pathways are central to the body’s defence against invading pathogens during pneumococcal meningitis. Whereas several studies support their importance in innate immunity, thereby preventing host mortality, any role in protecting neurological function durin...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Too, Lay Khoon, Yau, Belinda, Baxter, Alan G., McGregor, Iain S., Hunt, Nicholas H.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6838097/
https://ncbi.nlm.nih.gov/pubmed/31700009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52212-7
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