Pathogenicity of Clinical OXA-48 Isolates and Impact of the OXA-48 IncL Plasmid on Virulence and Bacterial Fitness

OXA-48 is the most common carbapenemase in Enterobacterales in Germany and one of the most frequent carbapenemases worldwide. Several reports have associated bla(OXA)(–)(48) with a virulent host phenotype. To challenge this hypothesis, 35 OXA-48-producing clinical isolates of Escherichia coli (n = 1...

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Udgivet i:Front Microbiol
Main Authors: Hamprecht, Axel, Sommer, Julian, Willmann, Matthias, Brender, Christina, Stelzer, Yvonne, Krause, Felix F., Tsvetkov, Tsvetan, Wild, Florian, Riedel-Christ, Sara, Kutschenreuter, Julia, Imirzalioglu, Can, Gonzaga, Aitor, Nübel, Ulrich, Göttig, Stephan
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6838017/
https://ncbi.nlm.nih.gov/pubmed/31736929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.02509
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