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Cross-talk between HPA-axis-increased glucocorticoids and mitochondrial stress determines immune responses and clinical manifestations of patients with sepsis

Various stressors activate the hypothalamo-pituitary-adrenal axis (HPA-axis) that stimulates adrenal secretion of glucocorticoids, thereby playing critical roles in the modulation of immune responses. Transcriptional regulation of nuclear genes has been well documented to underlie the mechanism of g...

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Detalhes bibliográficos
Publicado no:Redox Rep
Main Authors: Kasahara, Emiko, Inoue, Masayasu
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6837532/
https://ncbi.nlm.nih.gov/pubmed/25310535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1179/1351000214Y.0000000107
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