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Downregulation of IDH2 exacerbates H(2)O(2)-mediated cell death and hypertrophy
Objectives: Reactive oxygen species-mediated cell death contributes to the pathophysiology of cardiovascular disease and myocardial dysfunction. We recently showed that mitochondrial NADP(+)-dependent isocitrate dehydrogenase (IDH2) functions as an antioxidant and anti-apoptotic protein by supplying...
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| 發表在: | Redox Rep |
|---|---|
| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Taylor & Francis
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6837399/ https://ncbi.nlm.nih.gov/pubmed/26865387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13510002.2015.1135581 |
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