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Inhibition of neutral sphingomyelinase decreases elevated levels of nitrative and oxidative stress markers in liver ischemia–reperfusion injury

Oxidative stress and excessive nitric oxide production via induction of inducible nitric oxide synthase (NOS)-2 have been shown in the pathogenesis of liver ischemia–reperfusion (IR) injury. Neutral sphingomyelinase (N-SMase)/ceramide pathway can regulate NOS2 expression therefore this study determi...

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Detalhes bibliográficos
Publicado no:Redox Rep
Main Authors: Unal, Betul, Ozcan, Filiz, Tuzcu, Hazal, Kırac, Ebru, Elpek, Gulsum O., Aslan, Mutay
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6837382/
https://ncbi.nlm.nih.gov/pubmed/27077455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13510002.2016.1162431
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