Causal association between periodontitis and hypertension: evidence from Mendelian randomization and a randomized controlled trial of non-surgical periodontal therapy

AIMS: Inflammation is an important driver of hypertension. Periodontitis is a chronic inflammatory disease, which could provide a mechanism for pro-hypertensive immune activation, but evidence of a causal relationship in humans is scarce. We aimed to investigate the nature of the association between...

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Udgivet i:Eur Heart J
Main Authors: Czesnikiewicz-Guzik, Marta, Osmenda, Grzegorz, Siedlinski, Mateusz, Nosalski, Richard, Pelka, Piotr, Nowakowski, Daniel, Wilk, Grzegorz, Mikolajczyk, Tomasz P, Schramm-Luc, Agata, Furtak, Aneta, Matusik, Pawel, Koziol, Joanna, Drozdz, Miroslaw, Munoz-Aguilera, Eva, Tomaszewski, Maciej, Evangelou, Evangelos, Caulfield, Mark, Grodzicki, Tomasz, D'Aiuto, Francesco, Guzik, Tomasz J
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Fast Track Clinical Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6837161/
https://ncbi.nlm.nih.gov/pubmed/31504461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehz646
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