Challenging the workhorse: Comparative analysis of eukaryotic micro‐organisms for expressing monoclonal antibodies

For commercial protein therapeutics, Chinese hamster ovary (CHO) cells have an established history of safety, proven capability to express a wide range of therapeutic proteins and high volumetric productivities. Expanding global markets for therapeutic proteins and increasing concerns for broadened...

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Bibliografske podrobnosti
izdano v:Biotechnol Bioeng
Main Authors: Jiang, Hanxiao, Horwitz, Andrew A., Wright, Chapman, Tai, Anna, Znameroski, Elizabeth A., Tsegaye, Yoseph, Warbington, Hailley, Bower, Benjamin S., Alves, Christina, Co, Carl, Jonnalagadda, Kanvasri, Platt, Darren, Walter, Jessica M., Natarajan, Venkatesh, Ubersax, Jeffrey A., Cherry, Joel R., Love, J. Christopher
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
ARTICLES
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6836876/
https://ncbi.nlm.nih.gov/pubmed/30739333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.26951
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