Sophocarpine Suppresses NF-κB-Mediated Inflammation Both In Vitro and In Vivo and Inhibits Diabetic Cardiomyopathy

Diabetic cardiomyopathy (DCM) is a leading cause of mortality in patients with diabetes. DCM is a leading cause of mortality in patients with diabetes. We used both in vitro and in vivo experiments to investigate the hypothesis that sophocarpine (SPC), a natural quinolizidine alkaloid derived from a...

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Bibliographische Detailangaben
Veröffentlicht in:Front Pharmacol
Hauptverfasser: Zou, Fang, Wang, Ling, Liu, Han, Wang, Wei, Hu, Longlong, Xiong, Xiaoying, Wu, Lijuan, Shen, Yunfeng, Yang, Renqiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6836764/
https://ncbi.nlm.nih.gov/pubmed/31736745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01219
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