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A-to-I RNA editing contributes to the persistence of predicted damaging mutations in populations

Adenosine-to-inosine (A-to-I) RNA editing is a very common co-/posttranscriptional modification that can lead to A-to-G changes at the RNA level and compensate for G-to-A genomic changes to a certain extent. It has been shown that each healthy individual can carry dozens of missense variants predict...

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Bibliographic Details
Published in:Genome Res
Main Authors: Mai, Te-Lun, Chuang, Trees-Juen
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6836733/
https://ncbi.nlm.nih.gov/pubmed/31515285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.246033.118
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