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A-to-I RNA editing contributes to the persistence of predicted damaging mutations in populations

Adenosine-to-inosine (A-to-I) RNA editing is a very common co-/posttranscriptional modification that can lead to A-to-G changes at the RNA level and compensate for G-to-A genomic changes to a certain extent. It has been shown that each healthy individual can carry dozens of missense variants predict...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Mai, Te-Lun, Chuang, Trees-Juen
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6836733/
https://ncbi.nlm.nih.gov/pubmed/31515285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.246033.118
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