Nascent transcript analysis of glucocorticoid crosstalk with TNF defines primary and cooperative inflammatory repression

The glucocorticoid receptor (NR3C1, also known as GR) binds to specific DNA sequences and directly induces transcription of anti-inflammatory genes that contribute to cytokine repression, frequently in cooperation with NF-kB. Whether inflammatory repression also occurs through local interactions bet...

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Vydáno v:Genome Res
Hlavní autoři: Sasse, Sarah K., Gruca, Margaret, Allen, Mary A., Kadiyala, Vineela, Song, Tengyao, Gally, Fabienne, Gupta, Arnav, Pufall, Miles A., Dowell, Robin D., Gerber, Anthony N.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2019
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6836729/
https://ncbi.nlm.nih.gov/pubmed/31519741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.248187.119
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