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Assessment of the Inter-Batch Variability of Microstructure Parameters in Topical Semisolids and Impact on the Demonstration of Equivalence

Demonstration of similar microstructure is essential for demonstrating the equivalence of generic topical products since the microstructure of semisolids may affect the drug release. The objective of this study was to compare the microstructure-defining physical parameters of different batches of a...

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Publicado en:Pharmaceutics
Main Authors: Mangas-Sanjuán, Víctor, Pleguezuelos-Villa, María, Merino-Sanjuán, Matilde, Hernández, Mª Jesús, Nácher, Amparo, García-Arieta, Alfredo, Peris, Daniel, Hidalgo, Irene, Soler, Lluís, Sallan, Marta, Merino, Virginia
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6835722/
https://ncbi.nlm.nih.gov/pubmed/31581492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11100503
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