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Clarithromycin-Loaded Poly (Lactic-co-glycolic Acid) (PLGA) Nanoparticles for Oral Administration: Effect of Polymer Molecular Weight and Surface Modification with Chitosan on Formulation, Nanoparticle Characterization and Antibacterial Effects

Clarithromycin (CLR) is a member of the macrolide antibiotic group. CLR has low systemic oral bioavailability and is a drug of class II of the Biopharmaceutical Classification System. In many studies, using nanoparticles (NPs) as a drug delivery system has been shown to increase the effectiveness an...

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Detalhes bibliográficos
Publicado no:Polymers (Basel)
Main Authors: Öztürk, A. Alper, Yenilmez, Evrim, Özarda, Mustafa Güçlü
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6835525/
https://ncbi.nlm.nih.gov/pubmed/31600969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/polym11101632
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