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New opportunities for designing effective small interfering RNAs

Small interfering RNAs (siRNAs) that silence genes of infectious diseases are potentially potent drugs. A continuing obstacle for siRNA-based drugs is how to improve their efficacy for adequate dosage. To overcome this obstacle, the interactions of antiviral siRNAs, tested in vivo, were computationa...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Valdés, James J., Miller, Andrew D.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6834666/
https://ncbi.nlm.nih.gov/pubmed/31695077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52303-5
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