Global transcriptome analysis of rat hypothalamic arcuate nucleus demonstrates reversal of hypothalamic gliosis following surgically and diet induced weight loss

The central mechanisms underlying the marked beneficial metabolic effects of bariatric surgery are unclear. Here, we characterized global gene expression in the hypothalamic arcuate nucleus (Arc) in diet-induced obese (DIO) rats following Roux-en-Y gastric bypass (RYGB). 60 days post-RYGB, the Arc w...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Barkholt, Pernille, Rigbolt, Kristoffer T. G., Falkenhahn, Mechthilde, Hübschle, Thomas, Schwahn, Uwe, Fernandez-Cachon, Maria Luisa, Schmidt, Thorsten, Theis, Stefan, Hansen, Henrik H., Hay-Schmidt, Anders, Pedersen, Philip J., Vrang, Niels, Jelsing, Jacob
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6834618/
https://ncbi.nlm.nih.gov/pubmed/31695063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52257-8
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