Cyclophosphamide and fludarabine monophosphate dose optimization for the non-myeloablative condition in non-human primates to induce transient mixed chimerism via bone marrow transplantation

Bone marrow preconditioning using cyclophosphamide (CP) is generally used for bone marrow transplantation (BMT). However, because of CP’s hepatotoxicity and nephrotoxicity, additional fludarabine (FDR) administration and a reduced dose of CP are used for reduced-intensity preconditioning. Recently,...

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Bibliographische Detailangaben
Veröffentlicht in:Am J Transl Res
Hauptverfasser: Kwon, Yeongbeen, Lee, Kyo Won, Park, Hyojun, Son, Jin Kyung, Lee, JongHyun, Cho, Chan Woo, Kwon, Ghee Young, Park, Jae Berm, Kim, Sung Joo
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2019
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6834517/
https://ncbi.nlm.nih.gov/pubmed/31737196
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