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25-HC promotes hepatocellular carcinoma metastasis through up-regulation of TLR4 dependent FABP4

Metabolic syndrome is a significant risk factor for the development of hepatocellular carcinoma (HCC). 25-HC (25-hydroxycholesterol) synthesized from cholesterol plays an important role in lipid metabolism. However, the functions and mechanism of 25-HC in HCC remain largely unknown. In this study, w...

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Podrobná bibliografie
Vydáno v:Am J Cancer Res
Hlavní autoři: Wang, Saisai, Yao, Yuanyuan, Wang, Xiao, Zheng, Gang, Ouyang, Wei, Chen, Wenbin
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6834473/
https://ncbi.nlm.nih.gov/pubmed/31720079
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