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Systematic screening of 96 Schistosoma mansoni cell-surface and secreted antigens does not identify any strongly protective vaccine candidates in a mouse model of infection

Background: Schistosomiasis is a major parasitic disease affecting people living in tropical and sup-tropical areas. Transmission of the parasite has been reported in 78 countries, causing significant morbidity and around 200,000 deaths per year in endemic regions. The disease is currently managed b...

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Dettagli Bibliografici
Pubblicato in:Wellcome Open Res
Autori principali: Crosnier, Cecile, Brandt, Cordelia, Rinaldi, Gabriel, McCarthy, Catherine, Barker, Colin, Clare, Simon, Berriman, Matthew, Wright, Gavin J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: F1000 Research Limited 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6833992/
https://ncbi.nlm.nih.gov/pubmed/31728414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/wellcomeopenres.15487.1
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